Basic Information

Reference Number

0000277652

Issuing Organization

University of Ottawa

Owner Organization

University of Ottawa

Solicitation Type

RFP - Request for Proposal (Formal)

Solicitation Number

2024005-RES-RFP

Title

Instrument for Sizing and Concentration of Polydisperse Populations of Extracell

Source ID

PU.AC.ON.11752.C94742

Agreement Types

Broader Public Sector (BPS)

Canadian Free Trade Agreement (CFTA)

Details

Location

Canada, Ontario, National Capital Region

Delivery Point

TBD

Purchase Type

One Time Only- Delivery Date:TBD

Description

1. - Statement of Requirements

1.2.1. The Unversity of Ottawa is pleased to invite qualified proponents to submit a proposal for an instrument for sizing and concentration of polydisperse populations of extracellular vesicles and nanoprarticles. The requested instrument is a critical piece of equipment required to determine size and concentration of extracellular vesicle (EV) and nanoparticle preparations. The instrument ideally can distinguish subpopulations of nanoparticles or EVs in the size range of 20 nm to 1000 nm with minimal read times per sample and minimal variability. The instrument should measure individual particles to identify subpopulations with polydisperse sizes.

General Description:

The instrument will be capable of measuring the size of individual EVs and other nanoparticles ranging from 20 nm to 1000 nm and provide a reliable concentration of particles in solution in less than 10 minutes per sample. The instrument should be capable of measuring particles of different compositions including biological EVs, lipid nanoparticles, liposomes, gold or silver nanoparticles etc. The system will also be capable of differentiating subpopulations of EVs by size, by measuring large numbers of individual particles. Ideally, but not necessarily, the instrument may provide additional measurements of particles such as Zeta potential or fluorescence.

The instrument should be supplied as a fully operational instrument including all computers and software necessary. The instrument should allow for semi-automated size determination of particles ranging from 20 nm to 1000 nm and of concentrations of 5x107 particles/mL or lower and require minimal amounts of sample. The instrument ideally, but not necessarily, would have at least one laser capable of fluorescence measurement with an excitation wavelength of 488 nm, 520 nm, or 640 nm. Readings should be obtainable in under 10 minutes per sample following instrument calibration. More rapid and robust measurements would be an advantage.

The environment where the equipment will be placed is a regular lab at the University of Ottawa. The instrument footprint should fit within a space of approximately 2 feet by 2 feet not including an associated computer, and require a standard 120 V electrical outlet requiring less than 15A. A bench with minimal vibrations is available for the instrument. Service expectations are once per year during warranty period.

Disclosed Budget:
The University has a maximum total buget of $170,000.00 Canadian for the acquisition of, Instrument for Sizing and Concentration of Polydisperse Populations of Extracellular Vesicles and Nanoparticles. This budget include taxes, transportation, CSA certification and all other associated fees for this instrument.

Proponents are welcome to bid in other currencies as long they take into consideration the proposed budget. Financial evaluation will be evaluated based on the currency exchange rate of the day.

Specifications listed in Appendix A – Technical Specifications Compliance Form of this RFP are the mandatory minimum requirements for a nanoparticle tracking instrument for sudy of extracellular vesicles and nanoparticles.

Dates

Publication

2024/09/05 08:00:30 AM EDT

Bid Intent

Not Available

Question Acceptance Deadline

2024/09/12 03:00:00 PM EDT

Questions are submitted online

Yes

Closing DateA - Previous Amendment

2024/09/26 03:00:00 PM EDT

Contact Information

Ana Lopes

613-562-5800 ext. 2312

alopes@uottawa.ca

Buyer Preferences, Guidelines & Requirements

General Requirements

- Installation Required

- Training Required

- Warranty Information Required

Bid Submission Process

Bid Submission Type

Electronic Bid Submission

Pricing

In attached document

Bid Documents List

Item Name	Description	Mandatory	Limited to 1 file
Attachment #1	Technical/Qualitative Proposal and supporting documents as listed in section 2.3.4 in the RFP document	Yes	No
Attachement #2	Financial Proposal and supporting documents as listed in section 2.3.5 in the RFP document	No	No
No entries

Additional Bidding Instructions

1. - Proposals Submitted Only In Prescribed Manner

1. 1. The Proponent’s proposal must be submitted in the following manner:

1. 1. The Proponents must submit their proposal using Merx EBS no later than the time and date stated in section 2.2 – Timetable. No other forms of delivery will be accepted by the University.

The proposals must be complete and submitted in the prescribed format with the following information:

1. 1. The Proponent must provide two (2) separate attachments (files) containing the Proponent’s proposal labelled in the following manner:

Attachment #1 Technical/Qualitative Proposal: 2024005-RES-RFP_Insert Company Name
Attachment #2 Financial Proposal: 2024005-RES-RFP_Insert Company Name

1. 1. Attachment #1 – Technical/Qualitative Proposal must include the following mandatory documents:

Appendix A (Technical Specifications Compliance)
Appendix B (Rated Criteria)
Appendix C (Equipment, Utility, and Environmental Requirements) and all the referenced associated documents
Appendix D (Supplemental Information)
Appendix E (Reference Consent Form)
Appendix F (Submission Declaration Form)
Appendix H (Proponent’s Checklist Form)
All supporting technical documentation for the proposal
Detailed quotation without pricing
Bottom of every page of RFP initialled

1. 1. Attachment #2 – Financial Proposal must include the following mandatory documents:

Appendix G (Price Schedule Form)
Detailed quotation with pricing

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