Information de base

Numéro de référence

0000195300

Organisation émettrice

University of Ottawa

Organisation propriétaire

University of Ottawa

Type d’appel d’offres

DDP - Demande de proposition (Formel)

Numéro d’appel d’offres

36490-21A

Titre

BIOREACTOR FOR HIGH DENSITY GROWTH OF ADHERENT CELLS IN LARGE NUMBERS

Code d’identité d’origine

PU.AC.ON.11752.C94742

Types d’accord

Accord de libre-échange canadien (ALÉC)

Approvisionnement dans le secteur parapublic

Détails

Emplacement

Canada, Ontario

Point de livraison

451 Smyth Roger-Guindon Hall
ottawa, Ontario
Canada K1H 8M5

Type d’achat

Durée: TBD

Description

1. - Statement of Requirements

1.2.1.       The Unversity of Ottawa is pleased to invite qualified proponents to submit a proposal for a high density growth of adherent cells in large numbers. The equipment required is for sterile growth of adherent cells in media at a scale larger than standard research laboratory cultures in flasks, but smaller than industrial scale levels. The equipment should be capable of providing measures of media such as pH, temperature and oxygen levels in sterile conditions and is anticipated to require a media recirculation function.

                General Description:

The bioreactor for growth of adherent cells in media should be a scalable technology, with established cGMP-compatible protocols and the capacity for extensive control and reporting of cell culture conditions. The purpose of the equipment is to allow both research level production of cell and cell secreted products and establishment and optimization of processes for production of therapeutic cell and cell secreted products for small clinical trials.

The equipment should have the following specificiations:
1)             Accommodate 0.8-10 L or more of cell culture media
2)             Allow culture of adherent cells at high density likely by including systems to continuously recirculate media and sterilely replenish media
3)             Allow rigorous and reproducible control of cell seeding and cell growth conditions
4)             Allow adaptation to new types of adherent cells with minimal optimization of media and cell growth surfaces
5)             Allow easy separation of cell growth media from the bulk of cells.
6)             Allow monitoring and ideally recording of several cell culture conditions in a repeated fashion, ideally in an automated manner.
7)             Operate in a normal lab environment without the requirement for a sterile room
8)             Have a minimal footprint (ideally less than 1.5 m width, height or depth)
9)             Require minimal operator training time
10)           Have reasonably priced consumables

The environment that the equipment will be located in is a regular molecular and cell biology lab on the 3rd floor at the University of Ottawa in Roger Guindon Hall (451 Smyth Road). This room is equipped for other cell culture processes with biosafety cabinets and incubators. The equipment could be placed on the floor or on a standard laboratory bench, or shelf. If adapatations, such as an anti-vibration surfaces are required, these should be included in the proposal.

Specifications listed in Appendix A – Technical Specifications Compliance Form of this RFP are the mandatory minimum requirements for the Bioreactor for High Density Growth of Adherent Cells in Large Numbers.

Afficher davantage

Dates

Publication

2021-03-17 12h00:20 HAE

Intention de soumissionner

Non disponible

Échéance de la réception des questionsA - Rectificatif précédent

2021-03-23 15h00:00 HAE

Questions sont soumises en ligne

Oui

Date de fermeture

2021-04-01 15h00:00 HAE

Information du contact

Ana Lopes

613-562-5800 ext. 2312

alopes@uottawa.ca

Préférences, directives ou exigences de l’acheteur

Exigences générales

- Installation requise

- Assurances requises

- Formation requise

- Information sur la garantie obligatoire

Processus de soumission

Type de soumission

Soumission électronique

Fixation des prix

Dans un document attaché

Liste de documents de la soumission

Nom de l’item	Description	Obligatoire	Limité à un fichier
Attachment # 1 Technical Requirement	Technical/Qualitative Proposal	Oui	Non
Attachment # 2 Financial	Financial Proposal	Oui	Non
Aucune entrée

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