Basic Information

Reference Number

0000195300

Issuing Organization

University of Ottawa

Owner Organization

University of Ottawa

Solicitation Type

RFP - Request for Proposal (Formal)

Solicitation Number

36490-21A

Title

BIOREACTOR FOR HIGH DENSITY GROWTH OF ADHERENT CELLS IN LARGE NUMBERS

Source ID

PU.AC.ON.11752.C94742

Agreement Types

Broader Public Sector (BPS)

Canadian Free Trade Agreement (CFTA)

Details

Location

Canada, Ontario

Delivery Point

451 Smyth Roger-Guindon Hall
ottawa, Ontario
Canada K1H 8M5

Purchase Type

Duration: TBD

Description

1. - Statement of Requirements

1.2.1.       The Unversity of Ottawa is pleased to invite qualified proponents to submit a proposal for a high density growth of adherent cells in large numbers. The equipment required is for sterile growth of adherent cells in media at a scale larger than standard research laboratory cultures in flasks, but smaller than industrial scale levels. The equipment should be capable of providing measures of media such as pH, temperature and oxygen levels in sterile conditions and is anticipated to require a media recirculation function.

                General Description:

The bioreactor for growth of adherent cells in media should be a scalable technology, with established cGMP-compatible protocols and the capacity for extensive control and reporting of cell culture conditions. The purpose of the equipment is to allow both research level production of cell and cell secreted products and establishment and optimization of processes for production of therapeutic cell and cell secreted products for small clinical trials.

The equipment should have the following specificiations:
1)             Accommodate 0.8-10 L or more of cell culture media
2)             Allow culture of adherent cells at high density likely by including systems to continuously recirculate media and sterilely replenish media
3)             Allow rigorous and reproducible control of cell seeding and cell growth conditions
4)             Allow adaptation to new types of adherent cells with minimal optimization of media and cell growth surfaces
5)             Allow easy separation of cell growth media from the bulk of cells.
6)             Allow monitoring and ideally recording of several cell culture conditions in a repeated fashion, ideally in an automated manner.
7)             Operate in a normal lab environment without the requirement for a sterile room
8)             Have a minimal footprint (ideally less than 1.5 m width, height or depth)
9)             Require minimal operator training time
10)           Have reasonably priced consumables

The environment that the equipment will be located in is a regular molecular and cell biology lab on the 3rd floor at the University of Ottawa in Roger Guindon Hall (451 Smyth Road). This room is equipped for other cell culture processes with biosafety cabinets and incubators. The equipment could be placed on the floor or on a standard laboratory bench, or shelf. If adapatations, such as an anti-vibration surfaces are required, these should be included in the proposal.

Specifications listed in Appendix A – Technical Specifications Compliance Form of this RFP are the mandatory minimum requirements for the Bioreactor for High Density Growth of Adherent Cells in Large Numbers.

Dates

Publication

2021/03/17 12:00:20 PM EDT

Bid Intent

Not Available

Question Acceptance DeadlineA - Previous Amendment

2021/03/23 03:00:00 PM EDT

Questions are submitted online

Yes

Closing Date

2021/04/01 03:00:00 PM EDT

Contact Information

Ana Lopes

613-562-5800 ext. 2312

alopes@uottawa.ca

Buyer Preferences, Guidelines & Requirements

General Requirements

- Installation Required

- Insurance Required

- Training Required

- Warranty Information Required

Bid Submission Process

Bid Submission Type

Electronic Bid Submission

Pricing

In attached document

Bid Documents List

Item Name	Description	Mandatory	Limited to 1 file
Attachment # 1 Technical Requirement	Technical/Qualitative Proposal	Yes	No
Attachment # 2 Financial	Financial Proposal	Yes	No
No entries

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